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Tauroursodeoxycholic acid sodium

CAS No. 35807-85-3

Tauroursodeoxycholic acid sodium ( TUDCA )

Catalog No. M14231 CAS No. 35807-85-3

Tauroursodeoxycholic acid (TUDCA) is a neuroprotective bile conjugate; inhibits nuclear factor-kappa B (NF-κB) activation in glial cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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50MG 38 In Stock
100MG 52 In Stock
200MG 69 In Stock
500MG 107 In Stock
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Biological Information

  • Product Name
    Tauroursodeoxycholic acid sodium
  • Note
    Research use only, not for human use.
  • Brief Description
    Tauroursodeoxycholic acid (TUDCA) is a neuroprotective bile conjugate; inhibits nuclear factor-kappa B (NF-κB) activation in glial cells.
  • Description
    Tauroursodeoxycholic acid (TUDCA) is a neuroprotective bile conjugate; inhibits nuclear factor-kappa B (NF-κB) activation in glial cells; shows anti-inflammatory effect by inducing TGF-β pathway; inhibits TNFα-induced lipolysis.
  • Synonyms
    TUDCA
  • Pathway
    MAPK/ERK Signaling
  • Target
    ERK
  • Recptor
    Others
  • Research Area
    Metabolic Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    35807-85-3
  • Formula Weight
    521.69
  • Molecular Formula
    C26H44NNaO6S
  • Purity
    >98% (HPLC)
  • Solubility
    H2O: ≥ 39 mg/mL
  • SMILES
    CC(CCC(=O)NCCS(=O)(=O)[O-])C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)O)C)O)C.[Na+]
  • Chemical Name
    Ethanesulfonic acid, 2-[[(3α,5β,7β)-3,7-dihydroxy-24-oxocholan-24-yl]amino]-, sodium salt (1:1)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Romero-Ramirez L, et al. Neural Regen Res. 2017 Jan;12(1):62-63.
2. Xia W, et al. Mol Med Rep. 2017 Apr;15(4):1753-1758.
3. Rani S, et al. PLoS One. 2017 Apr 20;12(4):e0176071.
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